Green Oxidation of Indoles Using Molecular Oxygen over a Copper Nitride Nanocube Catalyst was written by Xu, Hang;Yamaguchi, Sho;Mitsudome, Takato;Mizugaki, Tomoo. And the article was included in European Journal of Organic Chemistry in 2022.Application of 4583-55-5 This article mentions the following:
Oxidative transformation of indoles is a promising approach for synthesizing valuable nitrogen-containing compounds; however, conventional methods use toxic oxidants and additives. Herein, authors report for the first time the catalytic oxidative trimerization and the oxygenative cleavage (Witkop oxidation) of indoles using mol. oxygen under additive-free conditions accomplished by a copper nitride nanocube (Cu3N NC) catalyst. The Cu3N NC catalyst exhibits excellent activity to produce various indolin-3-ones and 2-ketoanilides with high functional group tolerance. Owing to this excellent catalytic performance, the Cu3N NC catalyst is distinguished from the conventional copper catalysts, demonstrating the high catalytic potential of metal nitride in organic synthesis. In the experiment, the researchers used many compounds, for example, 5-Bromo-2,3-dimethyl-1H-indole (cas: 4583-55-5Application of 4583-55-5).
5-Bromo-2,3-dimethyl-1H-indole (cas: 4583-55-5) belongs to indole derivatives. Indole, first isolated in 1866, and it is commonly synthesized from phenylhydrazine and pyruvic acid, although several other procedures have been discovered. Moreover, it is known that it controls biofilm formation. However, the role of indole in the cell has not been fully elucidated.Application of 4583-55-5
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Indole alkaloid derivatives as building blocks of natural products from闂佽壈浜崹淇沜illus thuringiensis闂佽壈浜粋鍧闂佽壈浜崹淇沜illus velezensis闂佽壈浜粋鍧 their antibacterial and antifungal activity study,
Preparation of Indole Containing Building Blocks for the Regiospecific Construction of Indole Appended Pyrazoles and Pyrroles