Reaction of isocyanate with phthalaldehyde was written by Yamamoto, Iwao;Tabo, Yoshizo;Gotoh, Haruo;Minami, Toru;Ohshiro, Yoshiki;Agawa, Toshio. And the article was included in Tetrahedron Letters in 1971.Computed Properties of C14H11NO This article mentions the following:
Phthalimidines (I) are prepared by the reaction of phthalaldehyde (II) with aryl isocyanates ArNCO. Thus, an equimolar mixture of PhNCO and II is heated to give N-phthalimidine (III). Similarly prepared are I (Ar = o-tolyl, m-ClC6H4, o-ClC6H4). Probably, IV are intermediates. II is treated with PhN:C:NPh to give III. In the experiment, the researchers used many compounds, for example, 2-Phenylisoindolin-1-one (cas: 5388-42-1Computed Properties of C14H11NO).
2-Phenylisoindolin-1-one (cas: 5388-42-1) belongs to indole derivatives. Indole exists overwhelmingly in the 1H-indole form as do other simple indoles. Moreover, it is known that it controls biofilm formation. However, the role of indole in the cell has not been fully elucidated.Computed Properties of C14H11NO
Referemce:
Indole alkaloid derivatives as building blocks of natural products from Bacillus thuringiensis and Bacillus velezensis and their antibacterial and antifungal activity study,
Preparation of Indole Containing Building Blocks for the Regiospecific Construction of Indole Appended Pyrazoles and Pyrroles