An article Room-Temperature Benzylic Alkylation of Benzylic Carbonates: Improvement of Palladium Catalyst and Mechanistic Study WOS:000481979500011 published article about ORGANIC HALOGEN COMPOUNDS; NUCLEOPHILIC-SUBSTITUTION; SODIUM THIOSULFATE; CHEMICAL-DYNAMICS; DIPHOSPHINE LIGANDS; DIMETHYL MALONATE; INORGANIC IODIDES; X-RAY; BENZYLATION; COMPLEXES in [Kuwano, Ryoichi; Yokogi, Masashi; Sakai, Ken; Miura, Takashi; Won, Sungyong] Kyushu Univ, Fac Sci, Dept Chem, Nishi Ku, Motooka 744, Fukuoka, Fukuoka 8190395, Japan; [Kuwano, Ryoichi; Sakai, Ken] Kyushu Univ, Ctr Mol Syst, Nishi Ku, Motooka 744, Fukuoka, Fukuoka 8190395, Japan; [Sakai, Ken] Kyushu Univ, Int Inst Carbon Neutral Energy Res, Nishi Ku, Motooka 744, Fukuoka, Fukuoka 8190395, Japan; [Masaoka, Shigeyuki] Osaka Univ, Grad Sch Engn, Dept Appl Chem, Suita, Osaka 5650871, Japan in 2019.0, Cited 60.0. The Name is Benzyl Alcohol. Through research, I have a further understanding and discovery of 100-51-6. SDS of cas: 100-51-6
The palladium catalyst for the nucleophilic substitution of benzyl carbonates was improved by using 1,1′-bis(diisopropylphosphino)ferrocene (DiPrPF) as the ligand. The [Pd(eta(3)-C3H5)(cod)]BF4-DiPrPF catalyst allows the benzylic substitution with soft carbanions to proceed even at 30 degrees C, affording the desired products in high yields (up to 99% yield). Thermally unstable pyridylmethyl esters are employable as the electrophilic substrates for the benzylic alkylation with the improved catalyst. Furthermore, we investigated the mechanism of the catalytic benzylic alkylation by means of DiPrPF ligand. The palladium(0) complex bearing DiPrPF activates the benzylic C-O bond to form the (benzyl)palladium(II) intermediate at room temperature. The coordination mode of the benzyl ligand would be equilibrium between the eta(1)- and eta(3)-manner. The nucleophile would preferentially react with the eta(3)-benzyl ligand to give the desired product.
About Benzyl Alcohol, If you have any questions, you can contact Kuwano, R; Yokogi, M; Sakai, K; Masaoka, S; Miura, T; Won, S or concate me.. SDS of cas: 100-51-6
Reference:
Indole alkaloid derivatives as building blocks of natural products from Bacillus thuringiensis and Bacillus velezensis and their antibacterial and antifungal activity study,
,Preparation of Indole Containing Building Blocks for the Regiospecific Construction of Indole Appended Pyrazoles and Pyrroles